Vitamina b6 shqip Comments Vitamin B 6 is one of the B vitaminsand thus an essential nutrient. All forms except pyridoxic acid and pyritinol can be interconverted. PLP, the metabolically active form of vitamin B 6is involved in many aspects of macronutrient metabolism, neurotransmitter synthesis, histamine synthesis, hemoglobin synthesis and function, and gene expression.
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PLP generally serves as a coenzyme cofactor for many reactions including decarboxylationtransaminationracemizationelimination, replacement, and beta-group interconversion.
PLP is a required coenzyme of glycogen phosphorylasethe enzyme necessary for glycogenolysis to occur.
PLP trevor pierdere în greutate cow chop an essential component of enzymes that facilitate the biosynthesis of sphingolipids. In this reaction, serine is decarboxylated and combined with palmitoyl-CoA to form sphinganinewhich is combined with a fatty acyl-CoA to form dihydroceramide.
Dihydroceramide is then further desaturated to form ceramide. Vitamina b6 In addition, the breakdown of sphingolipids is also dependent on vitamin B 6 because sphingosinephosphate lyasethe enzyme responsible for breaking down sphingosinephosphateis also PLP-dependent. PLP has been implicated in increasing or decreasing the expression of certain genes.
Increased intracellular levels of the vitamin lead to a decrease in the transcription of glucocorticoids. Also, vitamin B 6 deficiency leads to the increased gene expression of albumin mRNA.
Also, PLP influences expression of glycoprotein IIb by interacting with various transcription factors. Kur duhet përdorur kompleksi i vitaminës B The result is inhibition of platelet aggregation.
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The RDA for pregnancy is 1. The RDA for lactation is 2. For children ages 1—13 years the RDA increases with age from 0.
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As for safety, Tolerable upper intake levels ULs for vitamins and minerals are identified when evidence is sufficient. ULs are defined the same as in US. For women and men ages 15 and older the PRI is set at 1.
For pregnancy 1. For lactation 1. For children ages 1—14 years the PRIs increase with age from 0. Adverse effects have been documented from vitamin B 6 dietary supplements, but never from food sources.
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Even though it is a water-soluble vitamin and is excreted in the urine, doses of pyridoxine in excess of the dietary upper limit UL over long periods cause painful and ultimately irreversible neurological problems. In severe cases, motor neuropathy may occur with "slowing of motor conduction velocities, prolonged F wave latencies, and slăbiți gleznele sensory latencies in both lower extremities", causing difficulty in walking. Symptoms among women taking lower doses have been reported.
For US food and dietary supplement labeling purposes the amount in a serving is expressed as a percent of Daily Value.
Vitamin B 6 is found in a wide variety of foods. The richest sources of vitamin B6 include fish, beef liver and other organ meats, potatoes and other starchy vegetables, and fruit other than citrus.
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Vitamin B 6 is absorbed in the jejunum and ileum by passive diffusion. With the capacity for absorption being so great, animals are able to absorb quantities much greater than necessary for physiological demands.
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The absorption of pyridoxal phosphate and pyridoxamine phosphate involves their dephosphorylation catalyzed by a membrane-bound alkaline phosphatase. The trapped pyridoxine and pyridoxamine are oxidized to pyridoxal phosphate in the tissue.
The products of vitamin B 6 metabolism are excreted in the urine, the major product of which is 4-pyridoxic acid. Several trevor pierdere în greutate cow chop have shown that 4-pyridoxic acid is undetectable in the urine of vitamin B 6 -deficient subjects, making it a useful clinical marker to assess the vitamin B 6 status of an individual.
A small amount of vitamin B 6 is also excreted in the feces.
The classic clinical syndrome for vitamin B 6 deficiency is a seborrhoeic dermatitis -like eruption, atrophic glossitis with ulcerationangular cheilitisconjunctivitisintertrigoand neurologic symptoms of somnolenceconfusion, and neuropathy due to impaired sphingosine synthesis and microcytic anemia due to impaired heme synthesis. Less severe cases present with metabolic disease associated with insufficient activity of eveniment de slăbire coenzyme PLP.
Po ku gjendet vitamina D3? Eshte mire te kemi sa me shume lajme mbi kujdesin per shendetin.